Ben Franklin at the end...
http://nymag.com/intelligencer/2018/02/americas-opioid-epidemic.html
Debilitating menstrual cramps...
https://www.smithsonianmag.com/history/inside-story-americas-19th-century-opiate-addiction-180967673/
She can't do that second adolescence in a half-century-old-body thing in this life.
https://www.everettclinic.com/blog/male-mid-life-crisis-why
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